SquarePants wrote:My understanding of Premarin is that are two concerns about using premarin alone.
1. The estrogens from Premarin and its metabolites produce an distribution of estrogens that have a greater affinity for the breasts than normally produced estrogens. I understand that this is suspected to be responsible for the increased risk in breast cancer from Premarin use.
2. Augmenting with estrogen without progesterone can cause estrogen dominance, causes a variety of problems.
This has been my understanding as well, and also my experience since I took Premarin alone for 13 years. It relieved my menopausal symptoms and problems, but caused some others too (weight gain, foggy thinking, memory loss).
SquarePants wrote:The bioidentical hormone explanation is that progestin isn’t the same as progesterone, but was synthesized and sold because it was patentable, while real progesterone was not.
I have heard this also, from both my doctor and DH's (both of whom are bHRT specialists).
SquarePants wrote:Testosterone therapy for men sounds like it should be pretty easy for a doctor to manage. However, it looks like most mainstream doctors do not have proper knowledge about this field. Female hormone therapy sounds more complicated.
For DH and I, the experience has been the opposite - his doctor has to test his blood much more frequently and make constant adjustments to his T dose, as well as adding/subtracting other supplements and pills to keep his estrogen levels low enough. There's the added worry of his blood thickening from the T as well so he needs to donate blood periodically to keep the red blood cell count balanced. For me, I've been seeing the doctor for a year now, and other than the initial blood test, he hasn't checked it again - he just asks how I'm feeling and bases his prescriptions on that. (I feel great, actually.
SquarePants wrote:My wife’s gynecologist is pretty mainstream. My hormone doctor works mostly with women with bioidentical hormone treatment.
My OB-GYN isn't too happy about my decision to discontinue the Premarin and use bioidenticals instead, simply because he feels they haven't been tested enough or used for enough years to know how they will affect women. DH's hormone doctor has told us he works with a fairly equal number of men and women for hormone treatment. He is an OB-GYN in a separate practice.
Since I started taking bioidentical estradiol, estrogen, testosterone, progesterone, and a thyroid medication all at the same time, I really can't pinpoint which of these is most responsible for my increased libido and overall better well-being. I also take Wellbutrin which affects my mood and thinking so some of it may still be due to that. The most noticeable change when I started the hormones and thyroid med, other than increased libido, was just a generally less tired feeling and a clearer mind. I had read that Wellbutrin often gives people memory loss and foggy thinking/difficulty concentrating so I thought maybe that was responsible, but that all went away once I started on the bHRT and thyroid med. Wellbutrin had also aided in my weight loss, but I lost even more
weight after I started on the bHRT too.