Since no actual users of this drug have replied, I'll share what little I know.
Vaginal atrophy is usually caused by low estrogen. DW had it after her hysterectomy/oophrectomy.
Looking at their web site, I see no reason to use it over estrogen. DW at first used Estrace, a topical estrogen that is not readily absorbed into the blood. It is expensive and does not solve the underlying problem of low systemic estrogen. She is now on bioidentical Hormone Replacement Therapy, taking two kinds of estrogen, testosterone, and progesterone, in the form of a topical cream which is absorbed into the blood. We are having the best sex of our lives